In the mid-1990s, University of Cambridge biochemists David Klenerman and Shankar Balasubramanian were trying to solve a fundamental problem: how to watch a single DNA polymerase molecule at work. Their approach used modified nucleotides, called reversible terminators, tagged with four different colors of fluorescent molecules. If one of these “terminators” was grabbed by the DNA polymerase and incorporated onto the replicating DNA strand, it would block the addition of any other bases until removed using a separate chemical reaction.
Windows Phone 7.8，图片来自 Windows Central最坑的一次是在所有 Windows Phone 7 手机都无法升级到 Windows Phone 8，包括刚刚推出不久的旗舰机型 Lumia 900。微软为这些用户提供一个折中方案：把 Windows Phone 7 升级到 Windows Phone 7.8。Windows Phone 7.8 仅会带来部分 Windows Phone 8 的新特性，比如可调整大小的磁贴和更新后的开始界面，并且 Windows Phone 8 的应用不能向下兼容到 Windows Phone 7，不过开发者只能选择分别为 Windows Phone 8 和旧系统（包括Windows Phone 7.8）开发对应版本。
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